1830 · Paris
by Denis, Prosper Sylvain
Paris: Chez les libraires qui tiennent les ouvrages de Medecine, 1830. Denis, Prosper Sylvain (1799-1863). Recherches expérimentales sur le sang humain considéré à l'état sain, faites pour déterminer les modifications aux quelles est sujette dans l'économie la composition de cette humeur, et apprécier les phénomènes physiologiques qui s'y rapportent. xvi, 358, [2]pp. Paris: Chez les libraires qui tiennent les ouvrages de médecine, 1830. 211 x 136 mm. (mostly uncut). Original printed wrappers, spine darkened and with a few splits. Dust-soiling, some foxing, blurry library stamp on title and wrapper, but, on the whole, very good. First Edition, and very rare on the market. The printed wrapper indicates that the book was available at bookstores in Paris, but according to the title page, Denis had the book printed, perhaps by a relative, Cl.-Fr. Denis, in the small town of Commercy, suggesting that the printing was small. Denis discovered the presence of cholesterol ("cholestérine") in the blood. This he announced on p. 110 of his Recherches expérimentales. Denis, together with Louis Lecanu and Félix Henri Boudet, was one of the early French researchers who "placed blood chemistry on a sound foundation" (Coley, p. 2173). Garrison-Morton.com 13909. N. Coley, "Early blood chemistry in Britain and France," Clinical Chemistry 47 (2001): 2166-2178. Rosenfeld, Four Centuries of Clinical Chemistry, p. 377. .
(Inventory #: 46623)